The Xifaxan Difference

Proven relief in clinical trials

Diarrhea and abdominal pain: Over 40% of people reported* relief of BOTH symptoms

Diarrhea: Over 70% of people experienced relief

Abdominal pain: Over 50% of people experienced relief

IMPORTANT SAFETY INFORMATION

The most common side effects for Xifaxan in IBS-D were nausea (feeling sick to your stomach) and an increase in liver enzymes.

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Relief that lasts an average of 10 weeks

  • In a third clinical trial, 2 weeks of treatment provided people who took Xifaxan with 6 to 24 weeks of relief from their symptoms of irritable bowel syndrome with diarrhea (IBS-D)
    • The average was 10 weeks of relief
  • People whose symptoms return after a period of relief can be treated with Xifaxan again up to 2 times
    • And if those symptoms return, they may not be as severe as they were previously

 

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*Patients in the clinical trials reported relief based on their daily observations of their symptoms. For abdominal pain, relief was defined as a ≥ 30% improvement from baseline in the weekly average abdomnial pain score derived from their daily symptom scores. For diarrhea, patients quantified their stool consistency. Patients achieving relief had a weekly mean stool consistency score <4 (loose stool) for ≥2 weeks during the month following 2 weeks of treatment.

INDICATION

XIFAXAN (rifaximin) 550 mg tablets are indicated for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.

IMPORTANT SAFETY INFORMATION - XIFAXAN (rifaximin) 550 mg tablets
  • XIFAXAN is not for everyone. Do not take XIFAXAN if you have a known allergic (hypersensitivity) reaction to rifaximin, any of the rifamycin antimicrobial agents, or any of the components in XIFAXAN.
  • If you take antibiotics, like XIFAXAN, there is a chance you could experience diarrhea caused by an overgrowth of bacteria (C. difficile). This can cause symptoms ranging in severity from mild diarrhea to life-threatening colitis. Contact your healthcare provider if your diarrhea does not improve or worsens.
  • Talk to your healthcare provider before taking XIFAXAN if you have severe hepatic (liver) impairment as this may cause increased effects of the medicine.
  • Tell your doctor if you are taking drugs called P-glycoprotein inhibitors (such as cyclosporine) because using these drugs with XIFAXAN may lead to an increase in the amount of XIFAXAN absorbed by your body.
  • If you are pregnant, planning to become pregnant, or nursing, talk to your healthcare provider before taking XIFAXAN because it is unknown if XIFAXAN can harm an unborn baby or nursing infant.
  • The most common side effects for XIFAXAN in IBS-D were nausea (feeling sick to your stomach) and an increase in liver enzymes.

Please click here for full Prescribing Information for XIFAXAN.

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Salix Pharmaceuticals
8540 Colonnade Center Drive, Raleigh, NC 27615  

The Xifaxan 550 mg product and the Xifaxan trademark are licensed by Alfa Wassermann S.p.A. to Salix Pharmaceuticals or its affiliates. The Gut Guy character is a copyright and trademark of Salix Pharmaceuticals or its affiliates.

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INDICATION

XIFAXAN (rifaximin) 550 mg tablets are indicated for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.

IMPORTANT SAFETY INFORMATION - XIFAXAN (rifaximin) 550 mg tablets
  • XIFAXAN is not for everyone. Do not take XIFAXAN if you have a known allergic (hypersensitivity) reaction to rifaximin, any of the rifamycin antimicrobial agents, or any of the components in XIFAXAN.
  • If you take antibiotics, like XIFAXAN, there is a chance you could experience diarrhea caused by an overgrowth of bacteria (C. difficile). This can cause symptoms ranging in severity from mild diarrhea to life-threatening colitis. Contact your healthcare provider if your diarrhea does not improve or worsens.
  • Talk to your healthcare provider before taking XIFAXAN if you have severe hepatic (liver) impairment as this may cause increased effects of the medicine.
  • Tell your doctor if you are taking drugs called P-glycoprotein inhibitors (such as cyclosporine) because using these drugs with XIFAXAN may lead to an increase in the amount of XIFAXAN absorbed by your body.
  • If you are pregnant, planning to become pregnant, or nursing, talk to your healthcare provider before taking XIFAXAN because it is unknown if XIFAXAN can harm an unborn baby or nursing infant.
  • The most common side effects for XIFAXAN in IBS-D were nausea (feeling sick to your stomach) and an increase in liver enzymes.

Please click here for full Prescribing Information for XIFAXAN.

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