XIFAXAN dosing is convenient,
not continuous1

Dr. Mark Pimentel

Executive Director, MAST Program at Cedars-Sinai Medical Center

Watch Dr. Pimentel discuss the dosing of XIFAXAN, as well as data based on clinical trials in adults with IBS-D.

XIFAXAN dosing is convenient, not continuous1

  • Just 2 weeks of treatment, not continuous daily prescription medication1
  • One 550 mg tablet 3 times a day with or without food1
  • Patients who experience recurrence can be retreated up to 2 times1

IBS-D = irritable bowel syndrome with diarrhea

Reference: 1. XIFAXAN [prescribing information]. Bridgewater, NJ: Salix Pharmaceuticals.


XIFAXAN® (rifaximin) 550 mg tablets are indicated for the reduction in risk of overt hepatic encephalopathy (HE) recurrence in adults and for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults.

  • XIFAXAN is contraindicated in patients with a hypersensitivity to rifaximin, rifamycin antimicrobial agents, or any of the components in XIFAXAN. Hypersensitivity reactions have included exfoliative dermatitis, angioneurotic edema, and anaphylaxis.
  • Clostridium difficile-associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, including XIFAXAN, and may range in severity from mild diarrhea to fatal colitis. If CDAD is suspected or confirmed, ongoing antibiotic use not directed against C. difficile may need to be discontinued.