Resources for patients and caregivers

Whether you’re a patient who’s been diagnosed with hepatic encephalopathy (HE) or a caregiver to a loved one who’s been diagnosed, these resources are available to help you with a variety of needs.


XIFAXAN Instant Savings Card

The XIFAXAN Instant Savings Card provides most eligible, commercially insured patients help with their monthly copays for XIFAXAN. Most eligible* patients with commercial insurance covering XIFAXAN may pay no more than $0 per month for their prescriptions.*

The XIFAXAN Instant Savings Card can be activated by calling 1-866-XIFAXAN (1-866-943-2926) and selecting option 1, or by clicking the link below.

Download or activate
$0 copay available for eligible commercially insured patients with coverage for Xifaxan

*Eligibility Criteria, Terms and Conditions: This offer is only valid for patients with commercial insurance, including commercially-insured patients without coverage for Xifaxan. Patients without commercial insurance are not eligible. Commercially-insured patients with coverage for Xifaxan will receive savings to reduce their copay to as little as $0. Commercially-insured patients without coverage for Xifaxan will receive savings off of retail price to reduce the out-of-pocket cost to as little as $50. Maximum benefits and number of uses apply. For information about the maximum benefits and number of uses please visit and/or call the helpline 1-866-XIFAXAN (option 1). Patient is responsible for all additional costs and expenses after application of the maximum benefits. You must activate this coupon before using it by visiting, calling 1-866-XIFAXAN, or texting PAYZERO to 24109. Message and data rates may apply. The full terms can be viewed at This offer is not valid for any person eligible for reimbursement of prescriptions, in whole or in part, by any federal, state, or other governmental programs, including, but not limited to, Medicare (including Medicare Advantage and Part A, B, and D plans), Medicaid, TRICARE, Veterans Administration or Department of Defense health coverage, CHAMPUS, the Puerto Rico Government Health Insurance Plan, or any other federal or state health care programs. This offer is only good in the USA at participating retail pharmacies. This offer cannot be redeemed at other locations, including government-subsidized clinics or facilities. This offer is not valid where otherwise prohibited, taxed, or otherwise restricted. Patient is responsible for reporting receipt of co-pay assistance to any insurer, health plan, or other third party who pays for or reimburses any part of the prescription filled using the co-pay card, as may be required. This offer cannot be combined with other offers. This card has no cash value. No other purchase is necessary. This offer is nontransferable. No substitutions are permitted. This card is not health insurance. You understand and agree to comply with the terms and conditions of this offer as set forth above. Salix Pharmaceuticals reserves the right to rescind, revoke, or amend this offer at any time without notice. This offer expires on December 31, 2019.


H.E.L.P. Support Guide

If your doctor has prescribed XIFAXAN for the ongoing management of overt HE, you may have questions. Download this guide to find answers and details on the HE Living Program (H.E.L.P.) text message support that is available to you and your caregivers. Text REDUCE to 90803 to sign up now* or click the download for more information. Habla español? Envíe REDUCIR al 90803 para registrarse.

Download the H.E.L.P. Support Guide

*At no cost with an unlimited texting plan; otherwise, message & data rates may apply. Message frequency determined by user. Text HELP to 90803 for help. Text STOP to 90803 to cancel at any time. For terms, visit

Hepatic Encephalopathy Symptom Checklist

Hepatic Encephalopathy Symptom Checklist

If you think you may have HE, this easy-to-use checklist can help you identify the signs of an HE episode. Simply download the document by clicking below, fill it out, and talk to your healthcare provider about any mental or physical symptoms you’ve noticed.

Download the HE Symptom Checklist

Hepatic Encephalopathy Hospital Discharge Guide

If you or a loved one were hospitalized for overt hepatic encephalopathy (HE), this guide can ease the transition to everyday life. It offers information about HE you should know before and after discharge from hospital.

Download The HE Hospital Discharge Guide