The most common side effect for XIFAXAN in IBS-D was nausea (feeling sick to your stomach), experienced by 3% of people in two clinical trials. In a third clinical trial, 2% of the people experienced nausea and 2% showed an increase in liver enzymes.
If you take antibiotics, like XIFAXAN, there is a chance you could experience diarrhea caused by an overgrowth of bacteria (C. difficile). This can cause symptoms ranging in severity from mild diarrhea to life-threatening colitis. Contact your healthcare provider if your diarrhea does not improve or worsens.
XIFAXAN is not for everyone. Do not take XIFAXAN if you have a known hypersensitivity to rifaximin, any of the rifamycin antimicrobial agents, or any of the components in XIFAXAN.
These are not all of the possible side effects of XIFAXAN. Call your doctor for medical advice about XIFAXAN side effects.
Please click here for full Prescribing Information for XIFAXAN.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.