Alterations in specific bacterial groups and microbial community diversity are known as gut dysbiosis.2 It is an imbalance in the ratio of harmful and helpful bacterial groups.2
The role of gut dysbiosis in IBS-D
Gut dysbiosis, or bacterial imbalance, has been linked to the symptoms of IBS-D that your patients may experience.1,4,5 Many studies have reported differences in the quality, quantity, and temporal stability of gut bacteria in patients with IBS-D compared to healthy individuals.2,3,6-10
Studies show that many patients with IBS-D have a bacterial imbalance in the gut1-3
As the body of evidence continues to grow in support of the link between gut dysbiosis and IBS-D, so too does the need for compatible pharmacologic therapies.
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