In a US clinical trial
The majority of IBS-D patients had an abnormal composition of bacteria in the gut1*
*This data comes from 62/93 patients from a prospective sub-study in TARGET 3.
What is gut dysbiosis?
Alterations in specific bacterial groups and microbial community diversity are known as gut dysbiosis.2 It is an imbalance in the ratio of harmful and helpful bacterial groups.2
Studies show that many patients with IBS-D have a bacterial imbalance in the gut3-5
Bacterial imbalance has been linked to symptoms of IBS-D3,6,7
Effect associated with bacterial imbalance
As the body of evidence continues to grow in support of the link between gut dysbiosis and IBS-D, so too does the need for compatible pharmacologic therapies.