ABOUT XIFAXAN

What is XIFAXAN (zī-fax-an)?

Xifaxan is a prescription treatment that helps you find relief from IBS-D symptoms of abdominal pain and diarrhea. It's the only FDA-approved two-week treatment for IBS-D.* With a short term treatment period and lasting relief, you can stop worrying about when your symptoms will strike† and start focusing on what matters.†

IBS-D = irritable bowel syndrome with diarrhea. *In a clinical trial: range of 6 to 24 weeks; average of 10 weeks. †You can be retreated up to two times if symptoms come back.

2-week treatment for up to 6 months of significant relief*†

*In a clinical trial: range of 6 to 24 weeks; average of 10 weeks.
†You can be retreated up to two times if symptoms come back.

There’s a different way to treat IBS-D

Unlike other IBS-D treatments, XIFAXAN is a short course therapy, without needing to take a continuous daily pill. XIFAXAN is a 2 week treatment that provides up to 6 months of relief from IBS-D symptoms. XIFAXAN works mainly in the gut to inhibit the growth of bacteria.*†

In clinical trials, patients reported that recurring symptoms were less severe than when they first started on XIFAXAN. Patients with recurring symptoms were treated with XIFAXAN up to 2 times.

The Gut Guy character

How does XIFAXAN treat IBS-D?

The exact cause of IBS-D is unknown. However, it is believed that an imbalance in gut bacteria may lead to IBS-D symptoms.

XIFAXAN works mainly in the gut to inhibit the growth of bacteria.

XIFAXAN is an antibacterial medication, or antibiotic, that did not cause any clinically relevant antibiotic resistance after 1 to 3 treatment cycles.

If you take antibiotics, like XIFAXAN, there is a chance you could experience diarrhea caused by an overgrowth of bacteria (C. difficile). This can cause symptoms ranging in severity from mild diarrhea to life-threatening colitis. Contact your healthcare provider if your diarrhea does not improve or worsens.

Most common side effects

In clinical studies, the most common side effects associated with XIFAXAN for IBS-D were:

• Nausea (feeling sick to your stomach)
• An increase in liver enzymes

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Taking XIFAXAN

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XIFAXAN is a short-term treatment that you take 3 times a day for 2 weeks

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Follow your doctor’s instructions exactly when taking XIFAXAN

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XIFAXAN tablets can be taken with or without food

Talk to your doctor about XIFAXAN

$0 copay available for eligible commercially insured patients with coverage for Xifaxan

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