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Get to the gut of your IBS-D. Take the quiz to find out.

Finding relief for your IBS-D* symptoms can be a long and frustrating process. Take our quick quiz to show your doctor and learn more about your options.

*IBS-D = irritable bowel syndrome with diarrhea.

*Based on aggregated total of all prescribers as of December 2020.

So many patients are finding relief from IBS-D with XIFAXAN

But don't just take it from us. Hear from real patients.

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IBS-D = irritable bowel syndrome with diarrhea.

Save on your prescription.

The XIFAXAN Instant Savings Card may help eligible,* commercially insured patients with coverage for XIFAXAN pay as little as $0—because your IBS-D has cost you enough.


*Patient is not eligible if he/she participates in, seeks reimbursement or submits a claim for reimbursement to any federal or state healthcare program with prescription drug coverage, such as Medicaid, Medicare, Medigap, VA, DOD, TRICARE, or any similar federal or state healthcare program (each a Government Program), or where prohibited by law. Patient must be enrolled in, and must seek reimbursement from or submit a claim for reimbursement to, a commercial insurance plan. Offer excludes full-cash-paying patients. Maximum benefits and other restrictions apply. Visit or call 1-866-XIFAXAN for full eligibility criteria, terms, and conditions.

Frequently asked questions about XIFAXAN

Below are questions patients may have about IBS-D and XIFAXAN. Always talk with your doctor about any concerns you have about your IBS-D symptoms and treatments.


How do I know if I have IBS-D?

If you experience diarrhea and abdominal pain on a regular basis, you may have IBS-D. Only a qualified healthcare professional can diagnose IBS-D, so discuss your symptoms with your doctor.
Connect with a doctor via telemedicine.

What is XIFAXAN?

XIFAXAN is a prescription antibiotic that works mainly in the digestive tract. XIFAXAN 550 mg tablets are indicated for the treatment of irritable bowel syndrome with diarrhea (IBS-D) in adults. It is a 2-week treatment. In a clinical trial, patients experienced up to 6 months of symptom relief from abdominal pain and diarrhea. You can be retreated up to 2 times if symptoms come back. Talk to your healthcare provider before taking XIFAXAN if you have severe hepatic (liver) impairment, as this may cause increased effects of the medicine.

In a clinical trial: average of 10 weeks; range of 6 to 24 weeks of relief from abdominal pain and diarrhea. You can be retreated up to 2 times if symptoms return.

What kind of relief can XIFAXAN provide?

XIFAXAN can provide lasting and significant relief of abdominal pain and diarrhea for up to 6 months. If you’ve been living with IBS-D symptoms, it may be time to talk with your doctor about XIFAXAN.

In a clinical trial: average of 10 weeks; range of 6 to 24 weeks of relief from abdominal pain and diarrhea. You can be retreated up to 2 times if symptoms return. Learn More

How can I learn more about XIFAXAN?

If you have additional questions about XIFAXAN or available resources and support, you can connect with a Navigator* today. Chat with a Navigator to learn more about XIFAXAN.


What should I do if I miss a dose?

Although you may feel better early in the course of treatment, XIFAXAN should be taken exactly as directed. Skipping doses or not completing the full course of therapy may (1) decrease the effectiveness of the immediate treatment, and (2) increase the likelihood that bacteria will develop resistance and will not be treatable by XIFAXAN or other antibacterial drugs in the future.

If my IBS-D symptoms come back, can I take XIFAXAN again?

If your symptoms return after a period of relief, you may find that they are not as severe as they were previously. But if your symptoms are bothering you, ask your doctor if another treatment with XIFAXAN may help provide IBS-D relief. You can be retreated up to two times if symptoms return.

Does XIFAXAN have any side effects?

The most common side effect for XIFAXAN in IBS-D was nausea (feeling sick to your stomach), experienced by 3% of people in two clinical trials. In a third clinical trial, 2% of the people taking XIFAXAN experienced nausea and 2% showed an increase in liver enzymes.

If you take antibiotics, like XIFAXAN, there is a chance you could experience diarrhea caused by an overgrowth of bacteria (C. difficile). This can cause symptoms ranging in severity from mild diarrhea to life-threatening colitis. Contact your healthcare provider if your diarrhea does not improve or worsens.

XIFAXAN is not for everyone. Do not take XIFAXAN if you have a known hypersensitivity to rifaximin, any of the rifamycin antimicrobial agents, or any of the components in XIFAXAN.

These are not all of the possible side effects of XIFAXAN. Call your doctor for medical advice about XIFAXAN side effects.

Please click here for full Prescribing Information for XIFAXAN.

You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit, or call 1-800-FDA-1088.

Can I take XIFAXAN with other drugs?

Tell your doctor if you are taking drugs called P-glycoprotein inhibitors (such as cyclosporine), because using these drugs while taking XIFAXAN may lead to an increase in the amount of XIFAXAN absorbed by your body.

XIFAXAN may affect warfarin activity when taken together. Tell your doctor if you are taking warfarin because the dose of warfarin may need to be adjusted to maintain proper blood-thinning effect.

Tell your doctor about all of the medicines you take including prescription medicines, over-the counter medicines, supplements or herbal medicines.


How can I access a doctor online?

With telemedicine, you can talk to a doctor from the comfort and privacy of your home at a time you choose. You can connect with a doctor online in just a few steps. (1) Answer some questions about your symptoms. (2) Connect directly to a licensed healthcare provider or schedule an appointment at your convenience to understand if your symptoms are IBS-D. (3) If diagnosed and prescribed a prescription, you may pick it up from your local pharmacy, or have it delivered. Connect with a doctor via telemedicine.

Download the resources you need

Get informed about XIFAXAN.

Our Patient Brochure has information to help you understand what XIFAXAN may do for you.

Start the conversation with your doctor.

The Discussion Guide helps you track your symptoms and prepare a list of questions.

Grab our Impact Guide for more info.

Our Impact Guide helps you get in-the-know about managing IBS-D.

Ready to talk to a doctor to see if XIFAXAN is right for you?

Finding relief for your IBS-D may seem like a lot of trial and error. If you’ve been unable to find relief from your IBS-D symptoms, take the next step and ask a doctor about XIFAXAN.